Practical Management of New Oral Anticoagulants

Question: Discuss about thePractical Management of New Oral Anticoagulants. Answer: Acute Massive Pulmonary Embolism (AMPE) Surgery and other associated conditions pose a risk of developing clots and eventually develop acute massive pulmonary embolism. The operations involving the pelvis, the hip, knee among others are the commonest associated with AMPE. During Mrs. Langleys Left total hip replacement surgery, the coagulation cascade is activated due to the incisions made. Since major veins like the iliac vein are close, the clots may have dislodged into these deep veins and carried to the lungs causing more than 50% blockage thus massive pulmonary embolism ("Pulmonary embolism," 2016). If the surgery cannot be avoided, then the patients are given anticoagulants like heparin to lower the risk of developing clots during the procedure. The anticoagulants suppress the function or synthesis of different clotting factors like factor VIII, IX, XII, XI, and thrombin (Klauser Dtsch, 2013). The anticoagulant will dissolve the clots in the veins and eventually relieve the symptoms like SOB and tachycardia. Moreover, the complications of AMPE like infarctions, brain death and loss of consciousness (LOC) shall be avoided resulting in shortened recuperation period after surgery (Klauser Dtsch, 2013). References Klauser, W. Dtsch, M. (2013). Practical management of new oral anticoagulants after total hip or total knee arthroplasty.Musculoskelet Surg,97(3), 189-197. https://link.springer.com/article/10.1007%2Fs12306-013-0306-8 Pulmonary embolism. (2016).Uptodate.com. Retrieved 26 September 2016, from https://www.uptodate.com/contents/pulmonary-embolism-beyond-the-basics#H24